WebJun 30, 2014 · TL;DR: The results suggest that the Nrf2/Maf binding-site-containing functional Cyp6a2 allele is associated with DDT resistance in the D. melanogaster strains under study. Abstract: BACKGROUND Increased insecticide detoxification mediated by cytochrome P450s is a common mechanism of insecticide resistance. Although Cyp6a2 … WebSep 25, 2024 · 本发明属于生物技术领域,具体涉及烟粉虱creb转录因子,以及编码基因和重组载体、重组细胞系、重组菌株,以及检测烟粉虱对吡虫啉抗性或敏感性的方法。背景技术烟粉虱bemisiatabaci(gennadius)是世界性的农业害虫,其危害主要包括直接刺吸植物汁液;传播植物病毒;分泌蜜露导致煤污病等。烟粉虱 ...
Nrf2/Maf-binding-site-containing functional Cyp6a2 allele is …
WebAlthough Cyp6a2 has been observed to be overexpressed in many 4,4′‐dichlorodiphenyltrichloroethane (DDT)‐resistant strains of Drosophila melanogaster, how Cyp6a2 is regulated and whether its overproduction confers DDT resistance remain elusive. WebFeb 15, 2024 · Compared to other alleles, Cyp6a2 Canton-S-1 lacks a 15bp fragment in the 5' core promoter region. This region forms part of a canonical binding site for the Nrf2/Maf heterodimer. The Cyp6a2 Canton-S-1 allele also has a 513-bp insertion of a 17.6 element in the 3' UTR. (Wan et al., 2014) in 2013 the world population was
Nrf2/Maf‐binding‐site‐containing functional Cyp6a2 …
WebMay 2, 2000 · Cyp6a2 and Cyp6a8 are downregulated in the hybrids of low and high producer strains Low level of expression appears to be the wild-type phenotype of both Cyp6a2 and Cyp6a8 genes because most strains show a low level of expression. Webthe Cyp6a8 and Cyp6a2 genes, respectively, has identified the presence of several putative AP1 binding motifs (Bhaskara et al., 2006). It is possible that caffeine induction of Cyp6a2 and Cyp6a8 genes may be mediated via the signaling pathways described above and the putative AP1 binding motifs. To test these possibilities and to WebMay 27, 2024 · In addition, we knew that CYP6A2 was able to metabolize ethoxycoumarin as well as diazinon, aldrin, and deltamethrin (, Amichot et al., unpublished data). Although we did not demonstrate that Cyp6a2 was an effector of adaptation to the for-controlled environment, we demonstrated here that for was able to modulate the expression level of … in 2016 in an illinois town called cahokia