WebOverview. Phospholipase C ß (PLC-ß)-coupled G protein-coupled receptor (GPCR) produce IP1, an analyte quantified by the IP-One assay. Purified IP1 can be used as a sandard to … WebIP-One ELISA assay kit from Cisbio Bioassays - Simple and highly accurate measurement of IP1 IP1, a downstream metabolite of IP3, accumulates in cells following activation of …
IP-One assay: the new solution for GPCR ... - Cisbio Bioassays
WebIP-One - Stimulation buffer Cisbio Home Life sciences G-protein signaling Gq signaling Stimulation Buffer 2 (5X) Stimulation Buffer 2 (5X) HTRF® 2:19 2:46 Stimulation Buffer 2 is spare part intended for use in the IP-One Gq … WebJan 1, 2006 · Abstract. Cisbio international has developed a complete cell-based platform to investigate G protein-coupled receptor (GPCR) activity. This article describes the three-step process to monitor GPCR ... curd edmonds
IP-One ELISA assay kit from Cisbio Bioassays SelectScience
WebCisbio’s platform includes IP-One, a very unique, non-isotopic assay and the best alternative to calcium flux assays. IP-One specifically measures IP-1 levels in cells. Over the past decade, IP-One has demonstrated its efficiency on numerous occasions for discovering and/or characterizing new compounds that target Gαq coupled GPCR. WebMar 28, 2024 · Ip-one, a new dimension in gq signaling Cisbio ip-one assays detect the accumulation of inositol monophosphate, a stable downstream metabolite of IP3 induced by activation of a phospholipase C (PLC) cascade. This Kit allows direct characterization of all types of compounds acting on gq-coupled receptors in either Adherent or suspension cells. WebA new secondary messenger for Gq coupled receptor investigation.Cisbio’s IP-One assay, based on its proprietary HTRF® technology, is the first HTS immunoassay that can easily detect inositol (1)phosphate (IP1), a stable second messenger which tightly correlates with Gq-coupled receptor activity. This assay displays all the characteristic ... curdella forbes ghosts review