Maf cell
WebDec 21, 2024 · Emerging evidence reveals that c-Maf expression programs the cytokine and metabolic profiles of tumor-infiltrating innate immune cells, including interleukin 17 (IL-17) … WebThe MAF gene (MIM 177075, NG_016440.1), homolog of an avian v-maf musculoaponeurotic fibrosarcoma oncogene, consists of 2 exons and encodes a basic …
Maf cell
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WebThe MH22B2 monoclonal antibody specifically recognizes human Interleukin-22 (IL-22), which is encoded by the IL22 gene. Cross-reactivity of MH22B2 mAb to mouse IL-22 (which shares 79% amino acid identity with human IL-22) has been observed by ELISA and by flow cytometry of HEK293 cells transfected with mouse IL-22 and TH17-differentiated CD4 … WebSep 30, 2024 · a The system for screening inhibitors of the c-Maf/Otub1 axis.b HEK293T cells expressing c-Maf, Otub1, and MARE.Luci were seeded in 96-well plates overnight and treated with 5 µM of each compound ...
Recently, Gabrysova L et al. demonstrated that TH17 response was inhibited in MafΔTcells mice in an experimental autoimmune encephalomyelitis (EAE) model6. This conclusion is not in line with our observation that MafΔTcells mice develop a colitis (Fig. 1C) characterized by the accumulation of TH17 cells … See more To study the role of Maf in T cells, we generated CD4cre Maffl/fl mice (MafΔTcells), in which all T cells (CD4+ and CD8+) are inactivated for the expression of Maf. Interestingly, these mice spontaneously … See more To confirm the results obtained in vitro, we first looked at the abundance of transcripts encoding for cytokines in the total colon of aged Maff/f or … See more We showed that both Treg differentiation and function were largely affected in MafΔTcells mice (Figs 3 and 4). To test whether the defect of MAF in Treg was sufficient to recapitulate the phenotype of colitis, we generated … See more The dramatic decrease in RORγt+ Treg was associated with an increase in classical RORγt− Treg in MafΔTcells mice (Fig. 3D). However, the development of spontaneous colitis … See more WebTranscription factor Maf also known as proto-oncogene c-Maf or V-maf musculoaponeurotic fibrosarcoma oncogene homolog is a transcription factor that in humans is encoded by …
WebApr 25, 2024 · c‐Maf enforces cytokine production and promotes memory‐like responses in mouse and human type 2 innate lymphoid cells The EMBO Journal Article25 April 2024 Open Access c-Maf enforces cytokine production and promotes memory-like responses in mouse and human type 2 innate lymphoid cells WebDec 2, 2016 · To further confirm the ability of MAF to confer resistance of RASm + cells to MEKi, we examined the sensitivity of MM RASm+/MAF to Tram.MTT assay showed that the IC50 of MM RASm+/MAF cells was 50% higher than that of MM EV cells (P <0.001). Similar results were observed in two other HMCLs with transient ectopic expression of …
WebMar 31, 2016 · The transcription factor c-Maf is extensively involved in the pathophysiology of multiple myeloma (MM), a fatal malignancy of plasma cells. In the present study, affinity chromatography and mass spectrometry were used to identify c-Maf ubiquitination–associated proteins, from which the E3 ligase HERC4 was found to …
WebApr 29, 2024 · Krausgruber et al. tested the epigenetic potential for immune gene activation in all three structural cell types upon viral infection. 1 On day 8 after intravenous injection of LCMV, up to 57.9% ... cso la ferroviariaWebMar 23, 2024 · You can open an MAF file in Microsoft Access to edit the form's fields and appearance, using Access's Form Layout Tools. ... (MAF), a file format used to capture … csola.ccWebInterleukin (IL)-10 is an essential anti-inflammatory cytokine that plays important roles as a negative regulator of immune responses to microbial antigens. c-Maf has been suggested as an essential transcriptional factor for IL-10 production in CD4 + T cells and macrophages. marco antonio samaniego lópezWebThis letter authorizes the Food and Drug Administration to include by reference information in our device master file, MAF #[specify the correct MAF number] for [specify the subject of the MAF, e ... csoka antonei cell phoneWebFeb 14, 2024 · The Maf (musculoaponeurotic fibrosarcoma) gene encodes the transcription factor c-Maf or MAF. Originally identified in natural musculo-aponeurotic fibrosarcoma of chickens infected with the replication-defective retrovirus AS42, the founding member of the Maf family, named v-Maf, was described as an oncogene ( 1 – 3 ). marco antonio sanchez riosWebApr 10, 2024 · mTORC2 controls thymic commitment of γδT17 cells via transcription factor c-Maf. mTORC2 deficiency results in impaired mitochondrial fission and ATP production. … marco antonio sanchez alvarezWebMAF is part of cluster 44 Myeloma - Humoral immune response with confidence i Confidence is the fraction of times a gene was assigned to the cluster in repeated … marco antonio salvo