Web23 Feb 2024 · HMBD-001 is a type of targeted cancer drug called a monoclonal antibody. It works by finding a protein on cancer cells called HER3. This protein is found in high numbers on some cancer cells. HMBD-001 attaches to the HER3 protein. This blocks the signals that cancer cells use to divide and grow. Researchers think this may slow cancer growth. Web5 Nov 2024 · The first-in-human phase 1/2 trial in HA (SIG-001-121, EudraCT 2024-004210-33) will assess the safety, tolerability and preliminary efficacy of SIG-001. This multi-center, open-label study with sequential, dose escalating cohorts, will enroll up to 18 participants (pts), including up to 3 initial pts per cohort and 3 additional pts if cohort expansion is …
001 File: How to open 001 file (and what it is)
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